Modeling of Competitive Flow in Aortofemoral Bypass

Competitive flow places surgical bypasses at risk for thrombosis in certain vascular beds, such as coronary bypass. However, the anatomic configurations that may lead to stagnation aortofemoral bypass remain poorly characterized. We aimed model competitive and determine parameters placing patency risk. created an dynamics computer using MATLAB software (MathWorks). Our standard (Fig 1) included a native iliac artery of 8 mm diameter with patent superficial femoral (SFA, 6 mm) profunda femoris (4 outflow conduit (8 positioned over artery. Models stenosis ranging from 0% 100% across four time points throughout arterial impulse cycle. Sensitivity analyses were performed SFA occlusion well varying graft diameters. total 40 models. Fig 2 shows our base increasing severity stenosis. As increases, arrives more briskly. With little or no stenosis, limb is delayed, but does not occur shown by aqua coloration moving through points. demonstrated similar findings. No portending high thrombosis. Computer modeling did demonstrate range configurations. models suggest put thrombosis.Fig 2Flow overlying inflow impulse.View Large Image Figure ViewerDownload Hi-res image Download (PPT)